Despite progress with experimental high-throughput techniques for the analysis of protein-protein interactions, bioinformatics, molecular modeling and simulation can play important roles in determining the stability and the structure of protein complexes, in identifying weak transient interactions, in understanding the role of non-functional interactions in a crowed molecular environment and in analyzing dynamic protein interaction networks.

Molecular biology, biochemistry, genetics, bioinformatics and molecular simulation all have important roles to play in understanding the complex protein networks that populate living matter. These networks in turn rely on protein-protein interactions that are characterized by structures, stabilities and lifetimes that vary over wide ranges and take place in a complex, heterogeneous and crowed environment.

The aim of the meeting is to provide an overview of protein-protein interactions, covering a range of scales: from physico-chemical analysis to prediction, from binary complexes to large assemblies, from cellular organization to the comparison of different organisms and from function to dysfunction and potential therapies.


Invited Speakers

Patrick ALOY                                Institute for Research in Biomedicine, Spain

Alexandre BONVIN                       Utrecht University, Holland

Elisa FADDA                                 Maynooth University, Ireland

Franca FRATERNALI                   King's College London, UK

Monika FUXREITER                     University of Debrecen, Hungary

Raphaël GUEROIS                       Institute of Integrative Biology of the Cell, CEA, France

Ozlem KESKIN                             Koç University, Turkey

Emmanuel LEVY                          Weizmann Institute of Science, Israel

Yanay OFRAN                              Bar-Ilan University, Israel

Rob RUSSELL                             University of Heidelberg, Germany

Julia SHIFMAN                             Hebrew University of Jerusalem, Israel

Peter UETZ                                   Virginia Commonwealth University, USA

Ilya VAKSER                                 University of Kansas, USA



Richard LAVERY IBCP, CNRS / University of Lyon

Juliette MARTIN IBCP, CNRS / University of Lyon

Alessandra CARBONE LCQB, CNRS / University P. et M. Curie, Paris




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